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Access to omics data has furthered our understanding of neurobiology, including the mechanics of early brain development and neurodegenerative conditions. Scientists have made good progress in unraveling the complex circuitry of neural pathways to identify potential gene and protein targets for drug discovery and development.
Technologies like single-cell and RNA sequencing make it possible to study the effects of genes and mutations in diseased and normal states, but we’re still missing key information about where specific types of cells are located and how they interact in a spatial and neural circuit context, which is critical for understanding their function. That’s why spatial omics is so exciting—these tools combine omics data with tissue images so that scientists can visualize gene and protein expression in a preserved tissue context. The technology is already being used in neuroscience and organismal development studies.
In this webinar, Xiangmin Xu, PhD, will introduce several single-cell and spatial multi-omics technologies and describe how they can be used to improve our mechanistic understandings of brain circuit plasticity and neurodegenerative diseases. You will also learn about the University of California Irvine (UCI) Center for Neural Circuit Mapping (CNCM), which has emerged as a hub for new technology and resource development in the field of neuroscience, and their efforts to develop single-cell spatial multi-omics tools.
A live Q&A session followed the presentation, offering a chance to pose questions to our expert panelist.
Professor, Dept. of Anatomy and Neurobiology
University of California, Irvine School of Medicine
Webinar produced with support from:
