Combinatorial CRISPR Screening and the Next Evolution in Functional Genomics

Genome-scale CRISPR screens in cancer cell lines have enabled the unprecedented identification of genome-scale vulnerabilities and co-dependencies. However, a significant obstacle in identifying co-dependencies is that the range of genomic features defines the discovery space. Therefore, it is clear that paired perturbations are needed to comprehensively map co-dependencies and establish functional genetic interaction maps. 

In this GEN webinar, our distinguished speaker, Dr. Manuel Kaulich, CSO of Vivlion and group leader at Goethe University, will show us how CRISPR gene editing and functional genetic screening can be used to identify co-dependencies and functional genetic maps, focusing on the key technological advancements that make human combinatorics possible. Additionally, we will learn more about Vivlion’s 3Cs technology, and its versatile applicability for minimized monogenetic and combinatorial CRISPR approaches.

A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelist.