Cancer Immunotherapy Spurs Work on Better Animal Models
GEN Spoke to Several Researchers on Advances in Engineered Animal Models Used to Study Novel Cancer Im-munotherapies
The Rise of Single-Cell Genomics
The Ability to Profile Single Whole Cells and Single Nuclei Will Also Help Shape Understanding of Each Cell Type
Philadelphia Project Gains STEAM
Artists Partner with Biotech to Inspire Young Scientists
Copy Number Variation Probes Inform Diverse Applications
Better Methods to Analyze and Organize DNA Fragments Are Emerging
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Molecular Pathway Transmits Itches, but Not Ouches
October 4, 2017
In this image, pain and itch sensory neurons are shown in red. [North Carolina State ... BNP is expressed in a small number of sensory nerve cells or neurons. The researchers knew ...
Obesity, Wasting Syndrome Both Wired into Hormonal Emergency...
October 2, 2017
GDNF family receptor a-like (GFRAL)-expressing neurons (yellow cells) are found ... Each drug acts on a molecular pathway that is localized in brainstem neurons. These ...
Disrupting Neuron and Glia Interaction Appears to Lead to Neurodegener...
September 29, 2017
between neurons and glia can result in neurodegeneration. Their study ("The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid ...
Cocaine Addiction Linked to Epigenetics
September 28, 2017
the team gave animals a form of HDAC5 that directly enters the nuclei of neurons. ... When the team analyzed which genes HDAC5 binds to in neurons, they identified NPAS4 as a ...
Solving the Puzzle of Cell Culture Optimization
September 15, 2017
... Loosely modeled after neural networks in the brain, artificial neural networks use interconnected nodes that imitate neurons to pass along information. According to Dr. Paul, the ...
Chip Reprograms Skin into Any Cell Type
September 1, 2017
epidermal skin cells into functioning neurons that within just a few weeks could be ... We have, for example, generated hundreds of thousands of neurons in the skin of mice. It ...
Histone Modification at Core of Epigenetic Control
September 1, 2017
... In neurons that encode information for memory, these molecular brake pads are engaged and ... cellular memory. "We reasoned that in neurons, changes via epigenetic mechanisms should ...
Eliminating Single Gene from Brain Appears to Increase Anxiety...
August 25, 2017
required for the differentiation of anxiolytic hypothalamic neurons in zebrafish and mice, although the identity of Lef1-dependent genes and neurons differ between these 2 species. ...
Loss of Circular RNA Throws Brain for a Loop
August 14, 2017
the gene for Cdr1as, a circRNA known to be predominantly expressed in excitatory neurons. ... They are part of the first wave of responses when stimuli are presented to neurons. Also ...
Alzheimer's Linked to Flaw in Lysosome Transport
August 7, 2017
It is not clear, however, how axons, the parts of neurons that conduct electric impulses, ... lysosome transport, they found that neurons that lacked a protein called JIP3 failed ...