The six-color naica® system is the industry’s first digital PCR system featuring six fluorescent channels, providing biomedical researchers and clinicians multiplexing and detection capacity. The system, which was designed to quantify circulating tumor cells (CTCs) and cell-free DNA (cfDNA) in liquid biopsies for oncology to detect low-level genetic variants in infectious diseases, uses microfluidic technology to integrate the dPCR workflow onto a single consumable chip. According to the the company, the technology, Crystal Digital PCR™, partitions samples into an extensive array of thousands of individual droplet crystals before amplifying nucleic acid molecules in each droplet crystal. These reactions are tagged with fluorophores to be read using up to six different fluorescence light channels.
