Endosafe® Trillium™ recombinant cascade reagent (rCR) cartridges from Charles River Laboratories were designed to provide an alternative option to bolster commitments to sustainability and animal welfare. The company is expanding its bacterial endotoxin testing (BET) portfolio with this new animal-free testing solution, which builds on Charles River’s existing Trillium rCR vial product. The company claims their test enhances testing efficiency and accelerates manufacturing timelines while simultaneously contributing to Charles River’s 4Rs imperatives (Replacement, Reduction, Refinement, and Responsibility) and further progressing their clients’ goals on sustainability and animal welfare.