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January 1, 2012 (Vol. 32 , No. 1)

Anion Exchange Media

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Bio-Rad Laboratories

Designed to meet the pressure-flow requirements of commercial-scale bioprocesses, Nuvia™Q high-capacity anion exchange media exhibits a binding capacity of greater than 170 mg/mL at a flow rate of 300 cm/hr. By maintaining high binding capacity even at fast flow rates, Nuvia Q can help improve productivity while reducing cycle time for downstream biotherapeutics purification. Moreover, less media is required for a given unit operation. Nuvia Q targets the purification of mAbs, recombinant proteins, and vaccines. When used for the intermediate polishing of mAbs, the media demonstrates high selectivity in the clearance of common contaminants in the feed stream such as dsDNA and host cell proteins.

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