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March 15, Vol. 27, No. 6

  • Feature Articles

    • Biomarket Trends: Proteomics Arrays Offer Wide A...
    • Jonathan Witonsky
    • Numerous technological advancements have been integrated into proteomics array technologies Enhanced surface chemistries combined with enlarged content menus are allowing manufacturers to develop proteomics arrays that are amenable to an extensive range of applications Today, proteomics arrays are commercially available ... more »
    • Cell Signaling Pathway Analysis
    • Patricia Fitzpatrick Dimond
    • Researchers are combining a range of techniques for analyzing key cell signaling pathways in drug discovery and therapeutic development, according to presentations at Cambridge Healthtech’s “Molecular Medicine Tri Conference” in San Francisco and a Keystone Symposium on “PI 3-Kinase Signaling ... more »
    • Evaluating Data Flow in Systems Biology
    • Kate Marusina
    • Systems biology is the study of the interactions between the components of a biological system and how these interactions give rise to the function and behavior of that system The objective is to model as many interactions as possible at ... more »
    • Chemogenomics Reveals New Synergies
    • Kathy Liszewski
    • Although not everyone agrees on the definition of chemogenomics, most believe the field holds great promise for the pharmaceutical industry In its broadest sense, chemogenomics describes how a chemical or family of compounds affects the genome At the end of ... more »
    • Protein Microarray Market Scope Broadens
    • Vicki Glaser
    • Multiplexed protein measurements using protein microarrays have several promising applications in drug discovery and clinical diagnostics These include delineating and interrogating signaling pathways and protein networks in health and disease states, enabling biomarker discovery and validation and use of biomarkers ... more »
    • Designing & Running Multiproduct Facilities
    • Gail Dutton
    • Although multiproduct manufacturing facilities have been in use for years, they are relatively rare for biologics processing As they increase, the need for speed, flexibility, and efficiency is putting them at the forefront of flexible manufacturing... more »
    • Ten Years After Dolly: Where Are We?
    • Sophia Fox
    • It has been more than 10 years since the birth of a lamb called Dolly knocked one of cell biology’s most entrenched principles on the head by providing living proof that a fully differentiated somatic cell nucleus could be reprogrammed ... more »