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January 1, Vol. 26, No. 1

  • Tutorials

    • Effective GPCR Screening Using ERK 1/2
    • G protein-coupled receptors (GPCRs) represent a diverse group of signaling proteins and are involved in a wide variety of physiological processes Of particular importance to the pharmaceutical industry, GPCRs, for the most part, have proved amenable as drugggable targets As ... more »
    • Maximizing Quality in HTS Kinase Screening
    • Protein kinases are enzymes that transfer a phosphoryl group to serine, threonine, or tyrosine side chains of a target protein, thereby changing its activity Dysregulation of protein kinases has been implicated in many types of cancer and also inflammation... more »
    • Taking the Guesswork Out of Production
    • Can our existing labor force handle a 20% increase in production? If the ultrafiltration step takes four hours longer than usual, how can the remaining process steps best be rescheduled to avoid interfering with the next batch? Does the flexibility ... more »