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April 1, Vol. 37, No. 7

  • Feature Articles

    • Fine-Tuning Efforts to Boost Immunotherapy
    • MaryAnn Labant
    • A growing recognition that both the innate and adaptive immune systems can play critical roles in antitumor activity continues to fuel activity in immuno-oncology research As new approaches emerge and enter clinical trials, the search continues to find ways to ... more »
    • CTCs Can Make Better Samples Than Biopsies
    • Lisa Heiden
    • Although circulating tumor cells (CTCs) and cell-free DNA (cfDNA) may be “bagged” in liquid biopsy samples, they may not stay intact through all the phases of an analytical workflow If these biomarkers suffer degradation—during storage, transportation, nucleic acid extraction, or ... more »
    • Cell-Therapy Production on Learning Curve
    • Angelo DePalma
    • The production of cells for cell therapy applications will reach industrial scale only after we expand our conception of bioprocessing Historically, bioprocessing has been understood as the harnessing of cells—the use of cells as means, not ends That is, cells ... more »
  • Columns

    • Checkpoint Inhibitors on the Inside Track
    • Gail Dutton
    • In January 2017, RXi Pharmaceuticals acquired MirImmune and launched itself into the immuno-oncology space Previously, RXi had explored dermatology and opthalmology As far-flung as these destinations may seem, they are all within reach of RXi’s self-delivering RNA interference (RNAi) technology, ... more »
    • Foldtec Successfully Produces Ab Fragment
    • Wacker Biotech and Fresenius Medical Care Adsorber Tec last month reached a key milestone in their collaboration by producing an scFv-class antibody treatment, which is used in apheresis products for selective dialysis Employing its E coli -based Foldtec ® technology, ... more »
    • Insights
    • Alexandria Real Estate Equities has selected its first member startup companies for the co-working space it plans to open in June within its urban campus for life science companies in New York... more »