Leading the Way in Life Science Technologies

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May 15, Vol. 25, No. 10

  • Feature Articles

    • Medicinal Chemistry Equals New Leads
    • Susan Aldridge, Ph.D.
    • Innovative approaches to medicinal chemistry in a number of important therapeutic areas were under discussion at Scientific Update's conference "MedChem Europe: Molecules that Matter" held in Berlin recently Smarter medicinal chemistry is key to getting new drugs on the market, ... more »
    • Cutting Through the Biomarker Hype
    • Elizabeth Lipp
    • Scientists trying to improve the productivity and efficiency of their drug discovery efforts still face issues of escalating R&D costs and the lengthy time it takes to conduct clinical trials As a result, biotech and pharma companies are looking at ... more »
    • Moving Toward System-Wide Software Suites
    • Gail Dutton
    • Electronic clinical trials are moving from standalone, point solutions toward software suites, similar to the way office applications migrated in the 1980s Eventually, investigators will have a seamless, system-wide software suite on a single platform that can handle every trial ... more »
    • Signal Pathways Making Inroads in Discovery
    • Signal pathways control a vast range of cellular events and keep cells operating cohesively Extracellular changes are communicated inside cells via cell-surface receptors, like tyrosine kinase, G-protein coupled receptors, and ion-channel receptors A signal-receptor complex triggers a cascade of protein ... more »
    • Growth of Virginia's Life Science Clusters
    • Strategically located near Federal institutions (like the National Institutes of Health) and regulatory agencies (like the Food and Drug Administration), Virginia is an ideal place for life science companies... more »
    • Preparation of Clinical Trials Materials
    • Contract preparation of clinical trial materials has been a growing business since the mid 1980s in Europe and the 1990s in the US, explains Gary Sutterlin, director of clinical trial project management at Cardinal Health (Philadelphia)... more »
  • Columns

    • Regulation of Combination Products by the FDA
    • Combination products, ie, those containing any combination of a drug, device, or biological, constitute a growing category of innovative medical products Examples include a drug with an implantable delivery device, drug-eluting cardiovascular stents, and autologous cells with scaffolds for orthopedic ... more »