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October 15, Vol. 31, No. 18

  • Feature Articles

    • Dementia Studies Making Strides
    • Vicki Glaser
    • Researchers from academia, pharma, and the biotech industry gathered at the National University Health System of Singapore last month for the “Translational Strategies for Therapeutics Discovery Through Dementia Biomarkers” conference... more »
    • Target-Enrichment Field Continuing to Expand
    • Richard A. Stein
    • As a result of recent progress in DNA sequencing technologies, which has generated datasets of unprecedented complexity and advanced our understanding of health, disease, and development, whole-genome sequencing has emerged as a highly anticipated goal However, routine sequencing of whole ... more »
    • GEN's 30th Anniversary: HIV/AIDS
    • The UNAIDS Report (2010) estimated that 333 million people worldwide were living with HIV/AIDS Sub-Saharan Africa accounts for 225 million of these individuals, while 15 million people with the disease live in North America... more »
    • Two Technologies Are Better Than One
    • Patricia Fitzpatrick Dimond
    • Caliper Life Sciences recently hosted a meeting where scientists described use of the company’s technologies to support high-quality drug candidate discovery and optimization The application of Caliper’s imaging technology, automation/liquid-handling robotics, and chip-based microfluidics technologies to meet and overcome technical ... more »
    • RNA Assumes More Prominent Role
    • Kathy Liszewski
    • RNA is beginning to take its place among the movers and shakers of biology For decades, it was considered a background player in biology, a static carrier of genetic instructions from big daddy DNA Now, however, RNA and its analysis ... more »
    • Single-Use Systems Growth Rate Plateauing
    • Eric S. Langer
    • Single-use bioreactors are making good progress at the commercial scale, with 433% of biomanufacturers using them, versus 683% at the scale-up/clinical production stage In this year’s 8th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production, we examined the ... more »
    • Tracking Key Biomanufacturing Trends
    • Cell culture media, novel resin technologies, and single-use systems are among the most active areas of R&D in the biomanufacturing sector GEN recently interviewed several scheduled speakers for the upcoming “Bioprocess International Conference” in Long Beach, CA, to get a ... more »
    • PCR-Based Diagnostics Put to the Test
    • Josh P. Roberts
    • PCR is a workhorse of biotech—whether it’s being used to prepare samples for another assay, or to assay samples from another preparation From the search for point mutations to discovery of methylated DNA biomarkers, homebrew tests can be crafted to ... more »
    • USP Improves Biologic Quality Standards
    • Tina Morris, Ph.D.
    • Once limited to a few naturally derived medicinal substances such as vaccines and blood products, biologics and biopharmaceuticals have come to encompass a diversity of treatments including recombinant proteins and enzymes, monoclonal antibodies, and gene-, cell-, and tissue-based therapies... more »