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February 1, Vol. 31, No. 3

  • Feature Articles

    • Cell-Based Assays Move to Fore
    • Josh P. Roberts
    • With an estimated 90% of lead candidates from in vitro screens ending up as also-rans—despite the spiraling costs of development—new ways of eliminating these candidates earlier in the drug discovery process need to be developed A major theme running through ... more »
    • Pfizer Retools Manufacturing Operations
    • Carol Potera
    • About two years ago, Pfizer acquired Wyeth to create what it says is the world’s largest biopharmaceutical company offering products in a variety of therapeutic areas Wyeth brought to the merger an early appreciation for biotechnology that led to biologics ... more »
    • GEN's 30th Anniversary: mAb Therapeutics
    • Monoclonal antibody products form one of the main pillars supporting R&D efforts as well as the very structure of the global biotechnology industry Market research company Visiongain has reported that the therapeutic monoclonal antibody market alone (not including diagnostics) led ... more »
    • Broadening the Focus of In Vivo Imaging
    • Vicki Glaser
    • At the American Society for Cell Biology’s annual meeting last month, Kat Hadjantonakis, PhD, an associate member of the Sloan-Kettering Institute, spoke about imaging live-cell dynamics in mouse embryos She described imaging experiments designed to shed light on cell lineage ... more »
    • In Vivo Imaging Product Showcase
    • In addition to the scientific presentations at the American Society for Cell Biology conference in Philadelphia, the exhibition floor featured a number of product offerings specifically designed for researchers studying the workings of the cell For example, Roche Diagnostics previewed ... more »
    • Dislodging Personalized Medicine Logjams
    • Rama Modali
    • Even though the technology of biospecimens have been around for over 150 years, today they are still vastly underutilized in the life science community With the decoding of the human genome and the rapid move to personalized medicine, the value ... more »
    • Engineer Solves His Second GEN Contest
    • Electrical engineer Owen Piette at Integrated DNA Technologies provided the winning answer to GEN’s latest “Cryptogram Challenge: qPCR” Owen, who with the help of a colleague also won the first GEN contest, “Microarray Challenge,” two years ago, figured out that ... more »