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November 01, 2008 (Vol. 28, No. 19)

Waging a Multipronged Alzheimer’s War

Numerous Targets for Small Molecule Drug Development Are Being Explored

  • Therapeutic drug discovery targeting Alzheimer’s disease (AD) is a wide open field, as this progressive neurodegenerative disorder presents various structural and biochemical abnormalities that could serve as drug targets. The etiologic origin for the amyloid-beta plaques and neurofibrillary tangles characteristic of AD remains unclear, and at present, therapeutic ...

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