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April 15, 2015 (Vol. 35, No. 8)

Variability Still an Issue for Culture Media

Chemically Defined Media Achieve Consistency, not Universality—Not without Supplements

  • Cell culture preferences have slowly shifted from serum-based to hydrolysate-supplemented to chemically defined. Dominant drivers for this trend have been a desire for consistency in product titer and quality, and a greater appreciation for process understanding. “The unexpected problem,” says Jon Wannlund, Ph.D., director of R&D for advanced ...

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