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February 15, 2014 (Vol. 34, No. 4)

MicroRNAs Leaping from Lab to Clinic

  • MicroRNAs (miRNAs) are small RNAs that regulate gene expression predominantly by inhibiting translation or promoting degradation of the target RNAs. Many dysregulated miRNAs are implicated in pathogenesis of various diseases. Such miRNAs have become a new hot topic in drug discovery and diagnostics. Several specific characteristics of miRNAs ...

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