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June 01, 2012 (Vol. 32, No. 11)

Downstream Bottlenecks More than Just Perception

  • One can barely discuss upstream bioprocess productivity without mentioning downstream process bottlenecks and their close cousin, the capacity mismatch. As my colleague Gail Dutton wrote in GEN in 2008, “the answer to whether a downstream bioprocessing bottleneck exists is largely one of perception.” Unlike the Easter Bunny, bottlenecks ...

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