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May 01, 2007 (Vol. 27, No. 9)

Building Better Pipelines with ADME-Tox

Advances in Microdosing, In Vitro Analysis, and Biosimulation for Optimized Predictive Studies

  • Realizing that a promising, effective drug has toxic side effects in humans, even if only in certain subpopulations, at certain doses, or in the presence of other drugs or co-morbidities, is a costly discovery, especially when it happens late in development. Even as such revelations continue to occur ...

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