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April 15, 2012 (Vol. 32, No. 8)

Bringing GPCR Research to the Fore

  • The group of seven transmembrane-spanning G protein-coupled receptors (GPCRs) represents the largest superfamily of receptors in the human genome. GPCRs are involved in virtually all physiological processes and represent the targets for at least 30% of all current medicines. GPCRs sense molecules outside the cell and, in response, activate ...

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