New Journal Details Applications, Technology Behind CRISPR Gene Editing
The CRISPR Journal Aims to Offer Original Research Papers, Commentaries, and Articles on Issues in the Field
Downstream Processing Builds Pure Intensity
Bioprocessing Favors Go with the Flow over Stop and Go
Top 15 Bioprocessing Companies
Manufacturing Grows Along with the Development of Biologics
Tumor Biomarkers Culled from Errant Transcripts
Potential for Blood Platelet–Derived Biomarkers to ID and Locate Tumors
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A Cellulose-Based Alkaline-Resistant Affinity Chromatography Resin Designed for the Industrial-Scale Purification of Monoclonal Antibodies
Therapeutic antibodies represent an innovative class of drugs used to treat a wide range of diseases such as rheumatoid arthritis and cancer Protein A chromatography resin is widely used in the production of therapeutic antibodies due to its high affinity and excellent selectivity for antibodies Utilizing our expertise in protein design and genetic engineering, we have made significant improvements to ‘Wild type’ or “Native’ Protein A ligand Immobilization of our improved Protein A ligand to highly cross-linked cellulose beads allows KANEKA KanCapA to exhibit alkaline resistance, stability over repeated cycle use, and to be used at high flow rates from laboratory to industrial scale with high binding capacity KanCapA exhibits excellent process development options, narrow pH elution for all monoclonal antibodies and non-binding Fab properties Mild pH elution avoids the formation of product aggregates Data presented here compares Kaneka KanCapA with already marketed PA resins and demonstrate the extremely high potential of KanCapA as the new PA , mAb purification platform...
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