The new Gibco Human Plasma-like Medium (HPLM) is described as the first cell culture medium that mimics the metabolic profile of human plasma and is designed to provide researchers with a realistic view of cell growth within the human body. Gibco HPLM, which contains the same salt concentrations found in human plasma and the same concentrations of over 60 polar metabolites, such as amino acids, nucleic acids, sugars, and small organic acids, was also designed to provide researchers the ability to study the impact of physiologically relevant cell media on their specific research applications, including cancer and other diseases. The company claims HPLM can support cell growth and viability that are comparable to that of conventional basal media formulations when supplemented with fetal bovine serum.