Expanding Cell Analysis in Cancer Research with Imaging Flow Cytometry
- Broadcast Date:
April 10, 2013
1 pm ET
10 am PT
7 pm CEST
- Broadcast Date:
April 11, 2013
REGISTRATION IS FREE
Imaging flow cytometry combines the speed, sensitivity, and phenotyping capabilities of flow cytometry with the detailed imagery and functional insights of microscopy. This unique combination has enabled a broad range of applications for cancer cell analysis that would be impossible using either technique alone.
In this webinar, Dr. Andrew Filby of The London Research Institute will describe the recent development of a novel method for reporting the cell cycle position and division history of asynchronously dividing cells. This method allowed detailed analysis of cell cycle inhibitor function down to the mitotic stage across multiple division rounds.
John Hazin of the German Cancer Research Center will describe how imaging flow cytometry expanded understanding of cell cycle and cell adhesion molecules in cancer biology in his laboratory. Hazin and his colleagues identified a subset of cells in which the transmembrane cell-adhesion molecule L1CAM (L1) forms polarized membrane domains. They further investigated the co-localization of other proteins with L1, as well as nuclear translocation of an intracellular L1 fragment believed to participate in signaling functions.
These examples demonstrate the practical use and the power of imaging flow cytometry.
What You Will Learn in This Webinar:
- How imaging flow cytometry facilitates analysis of highly heterogeneous samples and rare cell sub-populations
- How imaging flow cytometry allows simultaneous phenotypic and functional studies
- How imaging flow cytometry advances research of trans-membrane cell-adhesion molecules and analyzes their functionality in signaling complexes
Who Should Attend:
- Cell biologists
- Cellular immunologists
- Cancer cell biologists
- Cancer drug developers
- Membrane protein biochemists
- Cell signaling scientists
- Stem cell biologists
A live Q&A session will follow the presentations,
offering you a chance to pose questions to our expert panelists.