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GEN Presents An Educational And Informative Webinar

Leveraging Metabolites as Biomarkers for Personalized and Translational Medicine

  • Broadcast Date: Thursday, August 29, 2013
  • Time:



Estimates vary, but the time and cost of bringing a drug successfully to market at 12+ years and over a billion dollars, much of this being due to >95% failure rate. Lack of “translatability” is frequently cited as being at the root of the lack of clinical success. Overcoming translational barriers requires a deep understanding of human disease biology and biomarkers are needed to precisely define the key aspects of different disease or response characteristics. Only then, the correct populations can be selected, the right targets can be pursued, and preclinical models that match key aspects of disease can be designed. This is at the heart of translational or “precision” medicine.


This brief webinar will first navigate through the landscape and challenges in discovering biomarkers suitable for personalized and translational medicine. The journey continues with a walk through of the rational for why a systematic, discovery metabolomics approach is practical for addressing such challenges. Next, examples of how the approach has been applied to various disease research programs and the impact it has made. Lastly, the webinar walks through a specific case study demonstrating the usefulness of the approach and its impact on the successful development and commercialization of an innovative diagnostic to measure insulin resistance.


For additional questions or information, inquire at or visit our website at A complementary consultation is available anytime upon request.

A live Q&A session will follow the presentations, offering you a chance to pose questions to our expert panelists.



  • Dr. Bryan Whittmann,
  • Senior Study Director
  • Metabolon Inc.

Produced with support from