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Dr. James Wilson is a professor in the department of pathology and laboratory medicine, and the director of the gene therapy program, at the University of Pennsylvania. He is also the editor of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. During this interview with GEN, Dr. Wilson discusses his thoughts on whether recent developments in cell and gene therapy represent just another biotech bubble, or illustrate significant advances in the field.
In addition to this SKYPE interview, Dr. Wilson further elaborated on his view of the current status of cell and gene therapy in a column in the August 2013 issue of Human Gene Therapy which you can access by clicking here.
Employing CRISPR Technology in Drug Discovery
CRISPR technology will allow AstraZeneca to identify and validate new drug targets in preclinical models that closely resemble human disease.
Cas9: As a Transcriptional Activator
In this technical animation, Wyss Institute researchers instruct how they engineered a Cas9 protein to create a powerful and robust tool for activating gene expression.
Complex 3D DNA structures
MIT biological engineers have created a new computer model that allows them to design the most complex 3D DNA shapes ever produced, including rings, bowls, and geometric structures such as icosahedrons that resemble viral particles.
Top 10 U.S. Biopharma Clusters
Senior news editor Alex Philippidis discusses GEN’s annual ranking of the nation’s most nurturing regions.
Music in Your DNA and a New Species of Human?
Is musical ability genetic? And were there more species of ancient humans than we once thought? SciShow News investigates!
Could Tissue Engineering Mean Personalized Medicine?
Tissue engineer Nina Tandon talks about using pluripotent stem cells to make personalized models of organs on which to test new drugs and treatments, and storing them on computer chips.
The Science Love Song
Express your love this Valentine's Day with a scientifically accurate song by Mitch Moffit and Greg Brown from AsapSCIENCE.
Regenerative Medicine: Making the Impossible Possible
At the Center for Regenerative Medicine, researchers harness Mayo Clinic's collective knowledge, resources and skills to teach your body to heal from within and provide definitive solutions.
Will Gene Therapy Cure Cancer?
Jonathan Strickland walks through the process of human gene therapy, reveals it's exciting potential, and questions the ethics of genetic modification and altering DNA.
Synthetic Biology Explained
From selective breeding to genetic modification, our understanding of biology is now merging with the principles of engineering to bring us synthetic biology.