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GEN Webinars: January 01, 0001 (Vol. , No. )

Addressing the Challenges in Maintaining and Analyzing Biotherapeutic Glycosylation

<p> As the market for biopharmaceuticals continues to grow, manufacturers are increasingly challenged to improve their process efficiency while maintaining in vivo safety and efficacy profiles. Foremost of those challenges is minimization of batch-to-batch variability in product profile. Heterogeneous glycosylation patterns—a critical quality attribute (CQA)—as well FDA and EMEA mandates to demonstrate comparable glycan profiles represent daunting product consistency and analytical challenges. In this live webinar, we discuss the complexities of glycosylation, its implications in bioprocess development, and tools enabling precise control, quantitation, and characterization of glycan profiles. Our fully integrated solution of easy sample prep, high-throughput instrumentation, and glycan analysis-specific software offers a platform for streamlined solutions for biotherapeutic manufacturers.</p> <h3> Who Should Attend</h3> <ul> <li> Process development scientists</li> <li> Researchers interested in biosimilars development</li> <li> Innovative biopharma scientists</li> </ul> <p> <strong>You Will Learn About</strong></p> <ul> <li> Analytical challenges posed by glycan diversity</li> <li> Feed supplements designed to preferentially enrich specific glycan profiles and improve bioreactor utilization</li> <li> Analysis platform capable of glycan data acquisition from 96 samples in a work-day</li> <li> Strategies for glycoprotein purification and high-throughput analysis</li> </ul>