Instinct is redesigned control software for the Microlab Nimbus automated liquid-handling workstation. Instinct supports a range of daily lab work with new tools that can simplify and streamline programming. A built-in labware library displays an icon-based menu of micro- and deep-well plates, reagent troughs, and CO-RE (compressed O-ring expansion) disposable pipetting tips. Instinct’s Liquid Class Editor helps the user set pipetting parameters, while 3D graphics provide views of automatically created deck layouts. Instinct wizards walk the user through method creation steps for common routines such as serial dilutions, reagent additions, and plate replication.