The picoSpin 80, a portable NMR spectrometer that has a magnet rated at 2 Tesla, is designed to operate at 82 MHz and measure high-resolution spectra. This benchtop-scale instrument’s other features include a fluid capillary system, which is contained within a replaceable cartridge and requires only 40 microliters of a liquid sample. Because of this system, the instrument does not rely on NMR tubes or other consumables. In addition, the instrument’s temperature-controlled permanent magnet does not require cryogens. Spectra may be analyzed with bundled software, and the instrument may be monitored over a local network.