Related to Downstream Processing Issues Leveling Off

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• Bioprocess Performance Troubleshooting
• Spinnovation Biologics
• Spedia-Predict™ monitors and validates process-critical parameters to help manage the culture media consistency used in a production environment and can help to prevent failure and performance variability in large-scale commercial production. Spedi
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• Single-Use Chromatography System
• EMD Millipore
• The Mobius® FlexReady Solution with Smart Flexware® Assemblies for chromatography is a fully automated system designed to achieve good performance during the purification of biopharmaceutical products. This modular system features the abi
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• Nucleic Acid Sample Purification
• Roche
• The MagNA Pure 96 Instrument for nucleic acid sample purification can process up to 96 samples in less than one hour using barcoded, prefilled trays with ready-to-use reagents. Users can connect the MagNA Pure 96 Instrument to a laboratory informat
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• Chromatography Columns
• Phenomenex
• Yarra™ is a family of aqueous size-exclusion chromatography (SEC) columns for biomolecule analysis. Yarra columns are engineered to provide efficiency increases of up to 70% and higher resolving power. Yarra columns, offered in three phases with 3-
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• Sterile Sampling Bottles
• EMD Millipore
• The NovaSeptum® 125, 250, and 500 mL bottles are designed for sterile sampling from biomanufacturing processes. The bottles feature a single-piece cap with an O-ring component for container closure. This design can protect product integrity an
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• Modular Chromatography System
• GE Healthcare Life Sciences
• ÄKTA™ pure is a chromatography system for purification of proteins. It is a modular system that can support both routine and challenging purification requirements, as well as adapt to changing research needs. ÄKTA pure reduces the need fo
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• LC System
• AB Sciex
• The Eksigent ekspert™ nanoLC 400 system is a plug-and-play liquid chromatography system that integrates nano LC and micro LC on the same platform. This flexibility enables switching between high-sensitivity discovery proteomics and high-throughput
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• Peristaltic Pumps
• Watson-Marlow Pumps Group
• Profibus-enabled peristaltic pumps are designed for process monitoring in validated cGMP production. The Bp pump brings Profibus networking to peristaltic pumping; customers can integrate this seal-less, valve-less pump technology into their Profib
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• Pressure Gauge
• Ashcroft
• The DG25 digital pressure gauge provides a 5 full-digit LCD in ranges up to 25,000 psi. Available in accuracies of 0.5% and 0.25% FS, this design boasts a minimum battery life of 2,000 hours. Standard features include an IP67 enclosure, selectable
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• Polyethylene Bottom-Entry Mixer
• Terracon
• A new bottom-entry nonmetallic mixing tank is now available and is being offered in capacities up to 1,000 liters. All models include a cylindrical, cone-bottom molded polyethylene tank for ease of cleaning and complete drainage, as well as a magne
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• 10-Micron Chiral Media
• Phenomenex
• Lux™ Cellulose-1 and -2, complementary chiral stationary phases, are now available in 10-micron particle size for batch-preparative chromatography. The 10-micron particles are available both in Axia™-packed preparative columns, and in bulk, enablin
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• Lab Water Systems
• Thermo Fisher Scientific
• The Barnstead systems have been designed to meet the requirements of different customers’ applications. With a selection of systems providing multiple water types from a single source, Barnstead instruments enable customers to obtain pure or ultrap
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• Microcarriers for Bioprocess Scale-Up
• Corning B.V. Life Sciences
• A new line of microcarriers for large-scale vaccine and cell therapy manufacturing is now available. The microcarriers can simplify the scale-up of attachment-dependent cells by providing a premeasured, sterile, ready-to-use product for direct tran
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• Chromatography Media
• GE Healthcare Life Sciences
• Ni Sepharose™ excel is an immobilized metal ion affinity chromatography medium (resin) for the direct capture and purification of secreted histidine-tagged recombinant proteins from eukaryotic cell culture supernatants. The new resin can reduce sam
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• 5-Micron Core-Shell Media
• Phenomenex
• A 5-micron particle has been added to the Kinetex® core-shell product line. As the largest diameter particle in the family, Kinetex 5-micron core-shell columns can deliver better performance than 3- or 5-micron fully porous offerings, with no
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• Separation Columns
• Biotage
• Universal Phase Separators are fitted with a selectively permeable insert that separates aqueous phases from organic solvents under gravity; this can help remove an upper organic phase from a lower aqueous phase during a traditional liquid-liquid e
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• Chromatography Media
• Asahi Kasei Bioprocess
• TechniPur™ 40 μm ion exchange (IEX) chromatography media feature next-generation rigid agarose beads for biomolecule purification. TechniPur can reduce nonspecific interactions and provide greater capacity coupled with good mass transfer. In additi
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• Anion Chromatography Sorbent
• Pall Life Sciences
• The HyperCel™ STAR AX is a high-capacity anion exchange chromatography sorbent designed for high-salt solutions. Users can capture target protein directly from feedstock at conductivities of up to 15 mS/cm—no unit operations of ultrafiltration/difi
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• Peptide Chromatography Columns
• Waters
• Acquity UPLC® CSH130 C18 and XSelect™ HPLC CSH130 C18 columns allow for the analysis and purification of peptides and for the quality of information generated by UPLC, LC, and LC-MS assays. The synthesis process for the Charged Surface Hybrid
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• Bioprocess Capsules
• Pall Life Sciences
• SUPRAcap™ 50 capsules are designed to help you choose the right process-volume depth filter media. They are scalable to SUPRAcap 100 capsules or SUPRAdisc™ I/SUPRAdisc II depth filter modules and are also available with Seitz® HP sheet media (