Related to Firms Offer iPSC Cardiac Toxicity Screening

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• Cytotoxicity Assay
• Promega
• The Mitochondrial ToxGlo™ assay helps produce the predictive data necessary to assess mitochondrial function in the context of other cytotoxic events. Based on the differential measurement of biomarkers associated with changes in cell membrane inte
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• Compound Quality Control
• Brooks
• The Plate Auditor™ is a noninvasive tool for identification of precipitate and empty wells in compound and screening plates. The new Plate Auditor is the result of a collaboration with the Scripps Research Institute. It is designed to evaluate the
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• Stem Cell Culture and Differentiation Substrate
• Primorigen Biosciences
• Vitronectin XF™ is a defined xenobiotic-free cell attachment substrate for stem cell culture and differentiation. As a recombinant fusion protein containing the full-length human vitronectin sequence, Vitronectin XF is expressed in human cells unde
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• Hematopoietic Differentiation Medium
• Primorigen Biosciences
• The MesoTotal™ HPC/HSC differentiation system is a new medium and protocol for high efficiency differentiation of human pluripotent stem cells into hematopoietic progenitor cells (CD45/43+ and CD34+) and hematopoietic stem cells (CD45/43+, CD34+, C
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• 96-Well Plates
• Reinnervate
• The Alvetex® Scaffold 96-well plates allow scientists to grow tumor cells in a way that mimics the way these cells grow in vivo and test the cytotoxic effect of novel or existing anticancer compounds using standard cell health assays including
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• Stem Cell Lines
• Genea Stem Cells
• Embryonic pluripotent cell lines are available including one disease free pluripotent cell line and 24 others with individual mutations that can give rise to several severe diseases such as cancer (breast cancer, Wilm’s tumor, and Von Hippel–Lindau
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• Mitochondrial Toxicity Assays
• INDIGO Biosciences
• A new series of assays called the MitoVir platform evaluate mitochondrial toxicity by examining inhibition of the ribonucleoside triphosphates that are substrates for the human mitochondrial RNA polymerase (POLRMT). The MitoVir platform is based on
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• Kidney Toxicity Panels
• Bio-Rad
• Developed through a partnership with Myriad RBM, the Bio-Plex Pro RBM assays enable the detection of multiple biomarkers in a single sample, which may reveal damage within hours of kidney injury. This early detection can improve drug testing in bot
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• Hematopoietic Colony Imaging System
• STEMCELL Technologies
• STEMvision™ is a bench-top instrument and computer system designed specifically for automated imaging and counting of hematopoietic colonies in the colony-forming unit assay. This system is meant to be used with MethoCult™ media and meniscus-free S
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• Cardiomyocyte-Beat Monitor
• Roche
• The xCELLigence RTCA Cardio Instrument provides predictive information about cardiac safety during drug development by measuring cardiomyocyte beating under physiological conditions in cell culture. Through noninvasive, real-time monitoring in 96-w
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• Stem Cell Growth
• Life Technologies
• Gibco® KnockOut™ CTS™ SR Growth Factor cocktail and KnockOut CTS ESC/iPSC XenoFree kits enable feeder and feeder-free growth of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs). The KnockOut SR GF cocktail is sold
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• Stem Cell Culture Medium
• STEMCELL Technologies
• TeSR™-E8™ is a feeder-free culture medium for human embryonic stem cells (ES cells) and human induced pluripotent stem cells (iPS cells). TeSR-E8 contains only the essential eight components required for maintenance of ES cells and iPS cells. TeSR-
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• iPSC Media
• Life Technologies
• Existing feeder-free culture media can contain more than 20 interactive ingredients, many of which, such as bovine serum albumin (BSA) and lipids, are highly uncharacterized and vary significantly from lot to lot. Made in partnership with Cellular