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April 1, Vol. 28, No. 7

  • Feature Articles

    • Cancer Biomarkers Expedite Detection
    • K. John Morrow Jr.
    • It is widely acknowledged that early detection is the key to successful cancer treatment, yet such aggressive intervention requires accurate screening tools Traditional diagnostic tests for cancer have a number of drawbacks including poor sensitivity, lack of specificity, and costly ... more »
    • Regulations Still Driving Stability Testing
    • Angelo DePalma
    • While stability testing for small molecule drugs is well established, its counterpart for biologicals is still evolving Dozens of techniques have emerged for characterizing proteins, ranging from the standard and reliable (electrophoresis and chromatography), to the cutting edge (calorimetry), to ... more »
    • Revolutionizing Protein Expression in R&D Arena
    • Elizabeth Lipp
    • The expression of proteins for characterization, therapeutics, and diagnostics continues to be a challenging and complex task, requiring much time and untold expense The payoffs, though, are well worth it “Biomanufacturing is a multibillion dollar burgeoning industry,” noted Carlos Miguez, ... more »
    • Saskatchewan Looks Past AgBiotech Roots
    • Carol Potera
    • Located in Canada’s heartland, Saskatchewan is recognized for its agricultural biotechnology and livestock genomics With about half of Saskatchewan’s land devoted to agriculture, it’s not surprising that the province’s biotechnology companies have agricultural roots Phenomenome Discoveries , which specializes in ... more »
  • Columns

    • Defending Pharma Companies
    • J. Leslie Glick
    • Marc-André Gagnon’s point of view piece in the February 15 issue of GEN maintains that, by and large, pharmaceutical companies have departed from the mission of developing innovative therapeutics in favor of marketing me-too drugs so as to maximize earnings ... more »
    • Aging ELISA Realm Takes Benchmark Role
    • Christianne Bird
    • Very few assay formats on the market enjoy such a favorable reputation for performance, validation, and reproducibility as the ELISA In the fast-paced life sciences and drug discovery fields, the fact that a technique has survived nearly 40 years denotes ... more »
    • Increasing the Odds of In Vitro Fertilization
    • Carol Potera
    • While viewing an exhibit of Monet’s impressionistic paintings, Jim Posillico, Ph.D., president and CEO at Molecular Biometrics in Chester, NJ, noted the similarity of the art with his company’s metabolomics platform. Like the discrete brush strokes, textures, and colors that ... more »