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February 1, Vol. 28, No. 3

  • Feature Articles

    • Driving Discovery from Inside Out
    • Kathy Liszewski
    • In vivo imaging is rapidly gaining popularity as a faster and less expensive method for enhancing drug discovery and development Its keen ability to noninvasively gauge drug efficacy and trail compounds inside living organisms places it at the forefront of ... more »
    • qPCR Poised for Prime Time
    • Lloyd Dunlap
    • Hybridization microarrays, which have emerged as the leading quantitative tool for analyzing transcription of many thousands of genes in a sample simultaneously, have a number of limitations in analytical performance and sample throughput... more »
    • GEN’s Annual Wall Street Analyst Roundup
    • Even with the possibility (some would say it’s already a reality) of a recession in the US this year, the biotech stock analysts we interviewed for our Annual Wall Street Roundup feature express caution yet also optimism about the prospects ... more »
    • DNA Methylation Bolsters Cancer Research
    • Nina Flanagan
    • Globally, the epigenomics market is estimated to reach $41 billion by 2012, up from $2632 million in 2006, according to a March 2007 report by BCC Research The key market segments include research tools, cancer diagnostics, and cancer therapeutics Many ... more »
    • Winning the Contamination Control Battle
    • Angelo DePalma
    • Contamination issues continue to plague biomanufacturing even now, years after the Chiron (wwwchironcom) debacle in 2004 and 2005 In December 2007, Merck & Co (wwwmerckcom) voluntarily recalled one million doses of two vaccines: 11 lots of its Haemophilus influenzae type ... more »
  • Columns

    • Web Exclusive: GEN’s Annual Wall Street Roundup
    • Even with the possibility (some would say it’s already a reality) of a recession in the US this year, the biotech stock analysts we interviewed for our Annual Wall Street Roundup feature express caution yet also optimism about the prospects ... more »
    • New Act Endangers Long-Term Patent Validity
    • Beverly Lubit
    • For the third straight year, Congress has been considering patent reform in an attempt to legislate “high-quality patents” There is, however, no consensus as to what a high-quality patent really is The House passed legislation to overhaul US patent law ... more »
    • Company Update: Protagen Zeroes In on Protein Th...
    • Sophia Fox
    • When Protagen (wwwprotagencom) was awarded cGMP certification for protein analysis, it became one of a select group of protein products and service organizations capable of offering therapeutic protein manufacturers certified analyses of commercial batches of protein-based drugs, according to Christoph ... more »
    • Trubion Tackles Second-Generation mAbs
    • Carol Potera
    • Without a doubt, mAbs have been a therapeutic and marketing success for the treatment of cancer and inflammatory illnesses Nonetheless, their large size creates challenges such as limited tissue penetration and suboptimal antigen binding or biological response... more »