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March 1, Vol. 37, No. 5

  • Feature Articles

    • Glycosylation: Window into Quality
    • Angelo DePalma
    • Certain words and phrases—quality, safety, process optimization—will almost surely put you to sleep, unless you care about biosimilar production Then they might keep you awake at night Although biosimilar production may never let you rest easy, you can at least ... more »
    • Digital PCR Partitions and Conquers
    • Digital PCR (dPCR) can accurately determine the copy numbers of targeted nucleic acid molecules in a sample, without requiring comparisons to reference standards or endogenous controls, provided that many reactions are performed in parallel With this capability—along with others, including ... more »
  • Tutorials

    • Soluble Immune Checkpoint Markers
    • Ramona Seba
    • Immune checkpoint markers have been described as targets for therapeutic intervention because they play a role in the regulation of T cells, leading to either T-cell exhaustion or stimulation, which can modify antitumor immune response Antibodies such as the CTLA-4 ... more »