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October 1, Vol. 35, No. 17

  • Feature Articles

    • Molecules Hold the Mirror Up to Cancer
    • Kate Marusina
    • The molecular processes behind cancer were once seen as through a glass, darkly But now they are being reflected more clearly, thanks to advances in probe synthesis, preclinical cancer modeling, and multimodal imaging These advances have positioned imaging as a ... more »
    • Copy Number Analysis Starts to Add Up
    • Richard A. Stein
    • Collectively, copy number variants span more genomic material than all single nucleotide polymorphisms, and technological advances are increasingly unveiling their relevance for human biology, including disease predisposition and therapeutic and prognostic decision-making... more »
    • Twists and Turns in Protein Expression
    • Angelo DePalma
    • When drug developers use different cell lines for manufacturing and preclinical research, they risk generating inconsistent results, proteins with various structures and functions Then, confounded by variability, drug developers may lavish attention on irrelevant candidates and overlook promising candidates ... more »
  • Columns

    • LI-COR Focuses on Infrared Glow
    • Gail Dutton
    • LI-COR Biosciences, a 44-year old biotech hardware, software, and consumables company, grew out of an agronomy project, the development of light measurement devices for the study of photosynthesis Besides putting down roots in plant science, LI-COR branched out, pursuing opportunities ... more »
    • Evolving CMO-Sponsor Relationships
    • The relationship between sponsors and contract manufacturing organizations (CMOs) is being transformed slowly but surely, with true value added for sponsors, says Franco Negron, senior vp for the North American CMO business at Patheon “Years ago, the relationship was mostly ... more »
    • Advertorial: OriGene Technologies
    • OriGene Technologies was founded in 1996 as a research tool company focused on the creation of the largest commercial collection of full-length human cDNAs in a standard expression vector... more »
    • Advertorial: Solabia US
    • Present in pharmaceuticals, cosmetics, biotechnology, and microbiological diagnostics, the Solabia Group is characterized by 45 years of experience and a commitment to innovation and quality This is reflected in three R&D centers and four highly specialized production units, with two ... more »
    • Advertorial: Swift Biosciences
    • Swift Biosciences is transforming the next-generation sequencing (NGS) space by providing new technologies for sample and library preparation methods Based on their own unique and patented technologies, Swift enables researchers to use increasingly lower input amounts, which is important for ... more »
    • Advertorial: TangenX
    • TangenX Technology Corporation is a manufacturer of tangential flow filtration (TFF) products for use in applications in the biopharmaceutical industry, including our market-leading Sius™ Single Use TFF cassettes... more »