Leading the Way in Life Science Technologies

GEN Exclusives

More »

May 1, Vol. 35, No. 9

  • Feature Articles

    • A CRISPR Look at Genome Editing
    • Andrea Toell
    • Genome editing techniques have taken a giant leap forwards since the development of recombinant DNA technology back in the 1970s The ability to manipulate DNA revolutionized the field of biology, allowing researchers to study genes in hitherto unknown levels of ... more »
    • Could CRISPR Be the Magic Bullet?
    • MaryAnn Labant
    • The research community’s rapid acceptance of the CRISPR/Cas technology is propelling a stage of deep investment in technology development Already, three companies have emerged focusing on CRISPR therapeutic applications: Intellia Therapeutics, Editas Medicine, and CRISPR Therapeutics... more »
    • Repositioning Old Drugs for New Uses
    • Agnes Shanley
    • For years, pharma’s critics have decried the industry’s practice of “evergreening,” or extending drug patent life, arguing that it results in expensive and less innovative products However, the desire to wrest value out of drug development costs, pegged at $26 ... more »
    • Deciphering Immune Cell Chatter
    • Kathy Liszewski
    • Overseeing immune surveillance Driving cellular responses to changing environmental conditions Maintaining homeostasis These tasks are accomplished thanks to the complex network of intra- and intercellular communications... more »
    • Quality, Yield Still Rule Protein Production
    • Angelo DePalma
    • Uniformity is king when it comes to glycoforms Once the most effective, least immunogenic form is identified, bioprocessors seek processes that replicate this molecule within reasonable boundaries—the exclusion of fucosylation, maximum galactosylation, or specific sialylation patterns... more »