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December 1, Vol. 29, No. 21

  • Feature Articles

    • China Takes Aim at RNAi
    • Vicki Glaser
    • China-based companies, others with facilities or collaborative ventures in China, and academic groups all committed to advancing RNA-interference (RNAi) research and therapeutic drug development were well-represented at Select Biosciences’ “RNAi Asia” meeting held recently in Kunshan, China Most of the ... more »
    • Finding the Right Outsourcing Balance
    • Gail Dutton
    • Presenters and attendees at the “ChemOutsourcing” conference held recently in Long Branch, NJ, vigorously debated what should be outsourced and what should remain in-house This quandary is faced by most companies when they consider outsourcing chemistry development programs Firms also ... more »
    • Ireland Establishes Gastroenterology Base
    • Susan Aldridge, Ph.D.
    • Ireland is giving new meaning to the concept of the biotech cluster by building one that has an important therapeutic theme Gastroenterology Ireland seeks to bring together leading academics and gastrointestinal (GI)-focused drug discovery and development, drug delivery, and medical-device ... more »
    • Synthetic Bio Could Cure Energy Woes
    • Angelo DePalma
    • Craig Venter, PhD, of human genome fame and the Craig Venter Institute, created a stir with his August publication in Science of a technique for transferring a wholly engineered genome into a bacterium While it does not create artificial life ... more »
    • microRNAs Inform Cancer Research
    • Elizabeth Lipp
    • MicroRNA (miRNA) has a significant role in controlling developmental and cancer processes like cell proliferation, differentiation, cell cycle, apoptosis, and metastasis This ubiquitousness and their recently revealed role as key regulators of gene expression during development has boosted their use ... more »
    • Single-Use Systems Advance Filtration
    • K. John Morrow Jr.
    • Disposables for upstream and downstream processing were among the lead topics at IBC’s recent “BioProcess International” meeting held in Raleigh, NC In addition to their convenience and cost-reduction contributions, their use has been shown to result in reduced exploitation of ... more »
    • Assessment of Cell-Line Performance
    • Susan Aldridge, Ph.D.
    • Assessing the performance of a cell line is a crucial step in process development, and it can be done faster, cheaper, and more effectively by employing high-throughput small-scale technologies A seminar on the benefits of scaling down was recently sponsored ... more »
    • Neuroscience Benefits from Cash Infusion
    • Vicki Glaser
    • The scope and sheer volume of innovative research, fresh insights, next-generation technologies, and promising therapeutic opportunities presented at the recent Society for Neuroscience’s annual meeting in Chicago was more than any one, normal functioning brain could absorb, even with all ... more »
    • Stanching the Action of Anticoagulants
    • Bozena Korczak
    • Every day, surgeons are faced with the task of ensuring that their patients do not experience blood clotting during the invasive procedure Clots can be potentially life-threatening, since they can lodge in the brain and cause a stroke, or in ... more »