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September 1, Vol. 29, No. 15

  • Feature Articles

    • Innovation Marks Steady Growth of Asian Biotech
    • Gail Dutton
    • The conversation about outsourcing to Asia has changed from cost reduction to opportunity The recent BIOCOM “CalAsia Conference” in San Diego focused on strategies biotech companies can use to leverage the strengths of Asian biotech opportunities Presenters agreed that Asia ... more »
    • Live-Cell Imaging Increases Impact on R&D
    • Gail Dutton
    • Live-cell imaging technologies are providing what is often the first detailed look at intracellular interactions within living cells, yielding fresh insights into molecular functions and dynamic structures that may change within fractions of a second or during days of repeated ... more »
    • Next-Gen Presents Array of Opportunities
    • Elizabeth Lipp
    • Next-generation sequencing (NGS) has arrived “The expansion of users and applications shows no signs of abating,” notes Michael Rhodes, PhD, senior manager, SOLiD Sequencing at Applied Biosystems, a division of Life Technologies “The uptick of transcriptomics applications has been faster ... more »
    • Bioprocess Monitoring Relies on Connectivity
    • Angelo DePalma
    • Bioprocess monitoring and control, although not as widespread as it should be, is nevertheless increasingly viewed as a routine part of doing business Significant trends include interconnectivity between sensors, instruments, bioreactors, sampling systems, and software, collaborations among vendors to promote ... more »
    • Q&A on Sartorius Stedim Biotech/SAFC Deal
    • SAFC Biosciences and Sartorius Stedim Biotech recently signed a global partnership agreement that combines Sartorius Stedim Biotech’s expertise in filtration and liquid-handling systems with SAFC Biosciences’ proficiency in development and manufacturing of cell culture media and downstream purification products... more »
    • Changing the Face of Clinical Medicine
    • K. John Morrow Jr.
    • The annual “American Association of Clinical Chemistry” meeting is the largest conference focusing on the needs of the clinical laboratory This year the meeting expositions and presentations prominently featured multiplexing technologies and new strategies for developing biomarkers ... more »
    • MDx Hones In On Near-Patient Setting
    • Nina Flanagan
    • Molecular diagnostic advances are being driven by the need for automation and easy-to-handle techniques, said Mark Bunger, research director, biosciences at Lux Research Longer-term trends also driving this market include the influx of smaller companies developing diagnostic tools and a ... more »
    • Personalized Medicine Realizing Its Promise
    • Edward Abrahams
    • Personalized medicine may be considered an extension of traditional approaches to understanding and treating disease Physicians have always used observable evidence to make a diagnosis or prescribe a treatment tailored to each individual In the modern conception of personalized medicine, ... more »
  • Columns

    • EcoBiotics Scours Rainforest for Compounds
    • Carol Potera
    • Since 2000, EcoBiotics has been quietly combing the rainforests of Queensland, Australia, for new pharmaceutical compounds Now with two anticancer candidates in the late stages of preclinical testing, the company is expanding to the US and Europe Under the guidance ... more »
    • Choosing the Right Model
    • In all areas of clinical testing, peptide-based therapeutics have dramatically increased, nearly doubling from 2000 to 2007,” says Ralf Brandt, PhD, CEO and managing director of vivoPharm “However, many have failed due to lack of sufficient efficacy”... more »
    • Cellular Imaging and Analysis Roundtable
    • GEN recently sat down with thought leaders in the cellular imaging and analysis space to talk about current and emerging trends in the field The three experts, all intimately familiar with imaging applications, talked about the use of high-content screening ... more »
    • Emory University Named to NCI Chemical Biology C...
    • SAIC-Frederick, the prime contractor to the National Cancer Institute, selected Emory University’s Chemical Biology Discovery Center to be part of an 11-member national consortium aimed at accelerating the discovery and development of new and targeted cancer therapies... more »
    • Simplifying Antibody Conjugation Processes
    • Nick Gee
    • Antibodies are widely employed in the quantification of antigens in complex biological samples Using techniques such as Western blotting, ELISA, and immunohistochemistry researchers are able to measure a single antigen, or perhaps a limited number of antigens, in each sample ... more »