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Mar. 15, Vol. 29, No. 6

      • Madoff Matters, But Larger Issues Loom
      • Gail Dutton
      • In the months since financier Bernard Madoff was charged with promoting a Ponzi scheme, the financial repercussions continue to ripple. Charitable foundations lost millions of dollars, and the recipients of their endowments are feeling the pinch. ... more »
      • Maximizing Value in Outsourcing Services
      • Kathy Liszewski
      • The pharmaceutical industry is, without a doubt, feeling the crunch of skyrocketing costs, lackluster pipelines, and drug safety issues. Clinical professionals need to do more with less, while still maintaining the highest levels of quality. Many co ... more »
      • miRNA Profiling Opens Doors for New Drugs
      • Nina Flanagan
      • Many key biological processes are impacted by miRNAs, including cell growth and proliferation, tissue differentiation, embryonic development, and apoptosis. Mutation, dysfunction, and/or dysregulation of miRNA may lead to diseases like coronary arte ... more »
      • U.S. Biofuels Market Off and Running
      • Ellyn Kerr
      • Biofuels are already entrenched in the U.S. transportation fuels market, but not everyone may realize this. Yet, according to the Energy Information Association, by the end of 2008, U.S. ethanol facilities were producing up to 668,000 barrels per da ... more »
      • Dissecting Protein-Protein Interactions
      • Eric Sundberg
      • Nearly all cellular processes depend on protein-protein interactions. Therefore, understanding protein function and protein-protein interactions is key to gaining insights into the biochemical mechanisms that underlie disease and developing new drug ... more »
    • Corporate Profile

      • Honing In On Fatty Liver Disease Treatment
      • Joe Levit
      • In early January 2008, the National Center for Health Statistics released updated cardiovascular disease (CVD) mortality statistics based on data through 2005, the most recent year accurately completed. Though death rates from CVD declined 24.7% f ... more »
    • BioMarket Trends

      • Combating Hospital-Acquired Infections
      • Bruce Carlson
      • Hospital acquired infections (HAIs), also called nosocomial infections to better describe the range of places they can occur, have become a major health concern. In the U.S., between 5% and 10% of patients admitted to acute care hospitals acquire in ... more »
    • Assay Tutorials

    • Sidebars

      • China Gains in Innovative R&D
      • In discussing why his company recently opened a 60,000 sq-ft preclinical facility in Shanghai, Chris Perkin, corporate senior vp and president of Canadian and Chinese preclinical services at Charles River Laboratories, notes that China is rapidly “e ... more »
      • Determining Small Molecule Binding Kinetic Constants
      • Determining and evaluating the affinity of small molecule binding to a therapeutic target is a major component of drug discovery and lead optimization. In a technical note entitled “Label-free determination of kinetic constants for small molecule ... more »
      • GEN BIO Theater Presentations
      • GEN will sponsor a series of Theater presentations at the BIO Int’l Conference in Atlanta on May 19 and 20. The talks, which will take place at Booth 5807, will provide a venue for visitors in the exhibit hall to learn, at no cost, about the latest ... more »
      • Novel OncoMouse Model
      • Caliper Discovery Alliances & Services (CDAS), which offers multiple tumor models for preclinical cancer research, reports that it recently developed a pancreatic OncoMouse® model—EL1-luc/EL1-SV40 T-antigen transgenic—to overcome some disad ... more »

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GEN Poll

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Should “Special K” Get Special Treatment?

In the near term, what is the best way to use ketamine in treating depression?