GEN Exclusives

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Current Issue

Dec. 1, Vol. 34, No. 21
    • Point of View

      • Leaving Money on the Table
      • Phil Birch, D.Phil.
      • Many biotechs may be leaving money on the table. High-risk clinical evidence collection strategies can significantly devalue a development asset. Consider the issue of dose selection. The typical clinical trial only tests two or three plausibl ... more »
    • Feature Articles

      • GEN Roundup on Flow Cytometry
      • Flow cytometry has long been used in cell counting and cell sorting. More recent applications include biomarker detection, protein engineering, cell signaling, pathway screening, and systems biology. GEN recently interviewed a number of flow ... more »
      • Genomic Singularity Is Near
      • Kate Marusina, Ph.D.
      • The explosive growth of DNA-based diagnostics empowers us to take a closer look at our own health and to demand answers from healthcare providers to questions that have never been asked before. Even if we do not fully understand the ... more »
      • Special Report: Microarray Not Fade Away
      • Lisa Heiden
      • The microarray, the legacy technology for measuring gene expression, will not go gentle into that good night. True, in some respects, the microarray will be eclipsed by next-generation sequencing (NGS), specifically, whole transcriptome shotgun se ... more »
    • Corporate Profile

      • Refining Cellular Assays via Micropatterns
      • Gail Dutton
      • French contract research organization (CRO) Cytoo specializes in developing high-content, three-dimensional cellular assays for muscle and skin. It does so by means of micropatterns, which are initiated photolithographically and are ultimately ela ... more »
    • Bioprocessing Perspective

      • FDA’s Supply Chain Initiative
      • Title VII of the U.S. Food and Drug Administration’s Safety and Innovation Act (FDASIA) of 2012 seeks to quell the invisible hand that until now has guided sourcing and supply of raw ingredients and drug substances. The law, which is based on the ... more »
    • OMICS Tutorial

      • Comprehensive DNA Quantitation
      • Fabiola Saffache
      • With the advent of new technologies that aim to more clearly discern subtle and complex information from small samples, the requirement for setting quality control processes has never been greater. The need to determine sample concentration has pa ... more »
    • Drug Discovery Tutorial

    • Drug Discovery Tech Notes

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GEN Poll

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Should “Special K” Get Special Treatment?

In the near term, what is the best way to use ketamine in treating depression?