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January 15, Vol. 37, No. 2
  • Feature Articles

    • Snag-Free Combing of the Proteome
    • Richard A. Stein
    • Proteomics lags behind genomics and transcriptomics, endeavors that have been accelerated by next-generation sequencing Although proteomics isn’t exactly stuck—it is chugging along thanks to mass spectrometry (MS)—it sometimes spins its wheels because the world of proteins is particularly slippery... more »
    • Just Enough Downstream Innovation
    • Angelo DePalma
    • Platform manufacturing keeps driving the industrialization of bioprocessing, both upstream and downstream Upstream operations, risk averse as ever, are using the new platform approaches to do the usual: push raw production And it must be said that downstream operations are ... more »
    • Tuning Up or Taming Immune Responses
    • Kathy Liszewski
    • Sometimes standing up to a bully requires digging in and strengthening self-defense strategies Although the immune system is well-equipped to handle most assaults, a bully, such as an opportunistic pathogen or a crafty cancer cell, may overtake immunity... more »
    • GEN Roundup: Kinase Assays from Preliminary Scre...
    • Efficient kinase assays and precision medicine go hand in hand As precision medicine becomes more of a reality, researchers are taking a closer look at the role of kinase assays As an integral aspect of kinase inhibitor therapeutics and with ... more »
    • GEN Goes “Big” on Big Data
    • In this special section, we present four articles on Big Data. Each contains big ideas from a big player—Seven Bridges discusses precision medicine research in the million-genome era; Dell, the utilization of machine-learning capabilities; Qlucore, visualization for advanced Big ... more »