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Jul 31, 2014

Golgi—A Potential Drug Target for Alzheimer's Disease

In this literature review, the authors show how accumulation of amyloid beta peptides leads to Golgi fragmentation.

Golgi—A Potential Drug Target for Alzheimer's Disease

Golgi fragmentation in AD is caused by phosphorylation of Golgi structural proteins, which is induced by Aβ-triggered cyclin-dependent kinase-5 activation. [© psdesign1 - Fotolia.com]

  • First described in 1906 by Alois Alzheimer, Alzheimer's disease (AD) represents the most common form of dementia today and the sixth leading cause of ...

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Are the incursions of dengue fever and West Nile virus into North America just the tip of the iceberg of insect-borne diseases that are migrating due to a warming planet?