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May 13, 2013

Genome Sequencing and Patient Autonomy

In a dramatic shift away from the patient’s “right-not-to-know” message pervading clinical genetics since the field’s inception, new guidelines issued by American College of Medical Genetics and Genomics suggest that anyone undergoing genome sequencing for any reason should also be screened for dozens of variants associated with life-threatening but treatable conditions. (Read more about the new guidelines here.) What are your thoughts on this?

Do you think ACMG’s recent recommendations for reporting incidental clinical sequencing results undermine patient autonomy?


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