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GEN’s editor in chief, John Sterling, interviews life science academic and biotech industry leaders on important research, technology, and trends. These podcasts will keep you informed with all the important details you need.

A team led by researchers from The Scripps Research Institute has developed a new method for detecting functional sites on proteins. The technique may have broad applications in basic research and drug development, according to the scientists. Described online in Nature on November 17, the method enables scientists to take a sample of cells, locate the sites on their proteins that have a certain kind of biochemical reactivity, and measure the degree of that reactivity.


During this week’s podcast Dr Benjamin Cravatt III, senior investigator of the Nature study, describes how scientists currently try to detect functional sites on proteins and why a new approach is needed. He discusses the uniqueness of the newly developed protein screening technology and what it enables researchers to do now that they were not able to do in the past. He also talks about the range of patenting applications for the novel protein screening technique.

Dr. Benjamin Cravatt is currently professor and chair of the department of chemical physiology and co-director of the Center for Physiological Proteomics at The Scripps Research Institute. Dr. Cravatt’s research interests focus on developing and applying new technologies to elucidate the roles that enzymes play in physiological and pathological processes, especially as they pertain to the nervous system and cancer.


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