New treatments for secretory diarrheal disease are under investigation.

The Institute for OneWorld Health (iOWH) was awarded a $46 million from the Bill & Melinda Gates Foundation to expand its research on new treatments to complement traditional approaches for fighting diarrhea.


OneWorld Health’s research aims to develop new treatments for secretory diarrheal disease, particularly antisecretory drugs that inhibit the loss of fluid in the intestine. These drugs are designed to be used as an adjunct to oral rehydration therapy for the treatment of E. coli and cholera, which are responsible for nearly 40% of reported cases of diarrheal disease.

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