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April 15, 2015 (Vol. 35, No. 8)

Precision Tuning GPCR Pathways

The Cell, Like an Engine, May Need a Tune-Up for Optimal Performance, or Even a Smooth Idle

  • G protein coupled receptors (GPCRs) are essential drug targets for therapeutic intervention due to their integral roles in a plethora of fundamental signal transduction pathways. Indeed, GPCRs have a fruitful history in the pharmaceutical industry and are the targets of over half of all prescribed drugs today. Yet ...

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