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September 15, 2014 (Vol. 34, No. 16)

Phenotypic Drug Discovery in 3D

Testing Drug Efficacy by Rapid Size Profiling Over Time with Tumor Microtissues

  • It is commonly accepted that tumor sensitivity or resistance to chemotherapeutic agents is not only genetically determined, but also driven by the tumor microenvironment. Metabolic gradients and the extracellular matrix can influence nutrient availability to various segments of a solid tumor, and also limit the ability to administer an ...

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