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JB Therapeutics

  • JB Therapeutics
  • 508 Dudley Road
  • Newton Center MA, 02459

JB Therapeutics, a clinical stage biopharmaceutical company, is developing JBT-101 a nanomolar cannabinoid agonist which activates the CB2 receptor present on immune cells and fibroblasts. Upon binding CB2, JBT-101 stimulates the production of specific lipid mediators (PGJ2, LXA4) which act to turn off inflammation and fibrosis. The product is a pharmaceutical capsule containing a pure synthetic derivative of THC with minimal blood brain barrier penetration. It is currently being developed as a potential disease modifying treatment for the orphan disease scleroderma.

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