Metabolic engineering and directed evolution involve targeting and changing a microorganism's metabolic pathways to shed more light on how the pathways work or to redesign them to produce different types of products. A team led by Dr. Ryan Gill at the University of Colorado is developing new genetic and genomic tools, including microarrays, to improve our understanding of the evolution and engineering of relevant traits in bacteria of industrial and clinical relevance. The group is focusing on bacterial stress tolerance traits, which impact many applications, including industrial fermentations, bioremediation, and antibiotic resistance, among others.
This Weeks GENcast will give specific examples of how metabolic engineering and directed evolution can be used to improve a range of bioindustrial processes and highlight the importance of microarrays in this field of research.
After listening to the GENcast, you can give us your thoughts and opinions on the following question:
Do you think that research in industrial biotechnology requires different or modified forms of the microarrays that are currently used in other areas of life-science research?