Better Targeting, Delivery of RNAi Therapies
Forgoing the Comforts of Small Molecules and Antibodies, Some Drug Developers Are Setting Their Sights on RNAi-Based Therapeutics
Systems Biology Opens New Research Pathways
Systems Biologists Are Attacking the Encrypted Messages That Would Allow Us to Predict and Change the Course of Disease
Individual Tumor Profiling
Has Tumor Molecular Profiling Enabled More Effective and Less Toxic Cancer Treatment?
Top 10 Under 40
Up-and-Coming Stars Shine in Biopharma Research and Business
If, as the saying goes, “a stitch in time saves nine,” then a visit to STITCH2 online saves nine postdocs time. STITCH2 is a wonderful website to explore the interactions (both known and predicted) between proteins and chemicals. This site is a dream for anyone who enjoys exploring databases—there are five different search options (by name, chemical structure, protein sequence, multiple names, or multiple sequences) and 630organisms from which to choose. In total, the database includes interactions for more than 2.5 million (yes, million!) proteins and more than 74,000 small molecules. The search results are beautifully displayed as network diagrams in which one can click on each node for more information. Importantly, there are multiple viewing options. With the confidence view for example, stronger associations are represented with thicker lines. In evidence view, different colors denote various types of evidence for the associations.