Better Targeting, Delivery of RNAi Therapies
Forgoing the Comforts of Small Molecules and Antibodies, Some Drug Developers Are Setting Their Sights on RNAi-Based Therapeutics
Systems Biology Opens New Research Pathways
Systems Biologists Are Attacking the Encrypted Messages That Would Allow Us to Predict and Change the Course of Disease
Individual Tumor Profiling
Has Tumor Molecular Profiling Enabled More Effective and Less Toxic Cancer Treatment?
Top 10 Under 40
Up-and-Coming Stars Shine in Biopharma Research and Business
How often have we heard that video and computer games are eating away at the minds of youths today? Well here is one example of a computer game that most definitely does not fall into that category! With the tagline of “solve puzzles for science”, this game was most recently in the news a few months back when gamers solved the protein structure of a retroviral protease necessary for HIV replication. That’s right, folks—this is a game where the object is to find the “best” (i.e., most energetically favorable) conformation for real-life proteins. Players’ scores increase when the structure becomes more favorable, and decrease when the structure is less favorable. With sound effects and colorful graphics, this definitely feels like a game, rather than rigorous scientific work. And boy is it addictive! The downloadable game is available across Windows, Mac, and Linux platforms, and players can choose to play online or offline.